Advances in sequencing technologies and data analytics has brought about a new era in understanding and interpreting cells, DNA, RNA, and exosomes, which in turn has rapidly advanced our capabilities in diagnostics and therapeutics. The Molecular Biopsy stream at Next Generation Dx Summit gathers leaders, researchers, and experts in cell and DNA capture and microdissection, sequencing, data analysis, and interpretation to explore applications of molecular biopsy in clinical applications, their impact on the healthcare system, and future directions for diagnostic assay research and development.